Increased cellular proliferation in adipose tissue of adult rats fed a high-fat diet.

@article{Klyde1979IncreasedCP,
  title={Increased cellular proliferation in adipose tissue of adult rats fed a high-fat diet.},
  author={B J Klyde and Jules Hirsch},
  journal={Journal of lipid research},
  year={1979},
  volume={20 6},
  pages={705-15}
}
The feeding of a high-fat diet to adult rats was shown to increase the incorporation of [3H]thymidine into DNA of the adipocyte and stromal fractions. After only 2 days on a high-fat diet there was a marked increase in the incorporation of label. When a 2-week period was interposed between [3H]thymidine administration and determination of DNA specific activity, the greatest increase in incorporation of label was found after 1 week on the diet, when incorporation increased 6-fold or more in both… CONTINUE READING

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