Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini.

@article{Thuwajit2004IncreasedCP,
  title={Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini.},
  author={Chanitra Thuwajit and Peti Thuwajit and Sasithorn Kaewkes and Banchob Sripa and Kazuhiko Uchida and Miyu Miwa and Sopit Wongkham},
  journal={Parasitology},
  year={2004},
  volume={129 Pt 4},
  pages={455-64}
}
Infection by Opisthorchis viverrini is a strong risk factor for cholangiocarcinoma. However, the mechanism by which the parasite is involved in carcinogenesis is not clear. In addition to the direct damage of the bile duct epithelium via direct contact with O. viverrini, the excretory/secretory (ES) product(s) released from the parasites may play important roles in this process. We therefore investigated the responses of a fibroblast cell line, NIH-3T3, to ES product(s) released from O… CONTINUE READING