Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model.

@article{Jardine2005IncreasedCS,
  title={Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model.},
  author={David L Jardine and Christopher John Charles and Rachel Ashton and Sinclair I Bennett and Malcolm I. Whitehead and Christopher Miles Frampton and Michael Gary Nicholls},
  journal={The Journal of physiology},
  year={2005},
  volume={565 Pt 1},
  pages={
          325-33
        }
}
  • David L Jardine, Christopher John Charles, +4 authors Michael Gary Nicholls
  • Published in The Journal of physiology 2005
  • Medicine
  • The time course of cardiac sympathetic nerve activity (CSNA) following acute myocardial infarction (MI) is unknown. We therefore undertook serial direct recordings of CSNA, arterial blood pressure (MAP) and heart rate (HR) in 11 conscious sheep before and after MI, and compared them with 10 controls. Conscious CSNA recordings were taken daily from electrodes glued into the thoracic cardiac nerves. Infarction was induced under pethidine and diazepam analgesia by applying tension to a coronary… CONTINUE READING

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