Increased bone formation and decreased bone resorption in fetal mouse calvaria as a result of intermittent compressive force in vitro.

@article{KleinNulend1987IncreasedBF,
  title={Increased bone formation and decreased bone resorption in fetal mouse calvaria as a result of intermittent compressive force in vitro.},
  author={Jenneke Klein-Nulend and Jean Paul Veldhuijzen and Marion de Jong and Elisabeth H. Burger},
  journal={Bone and mineral},
  year={1987},
  volume={2 6},
  pages={
          441-8
        }
}
We have shown earlier that hypertrophic chondrocytes of growth plate cartilage in vitro react to an intermittent compressive force (ICF) of physiological magnitude by an increased calcification of the matrix. In this communication, we report the influence of ICF on bone metabolism, i.e., osteoblastic and osteoclastic activity, using fetal mouse calvaria in vitro. Seventeen-day-old calvaria were cultured for 5 days under control conditions (atmospheric pressure), or under the influence of ICF… CONTINUE READING

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