Increased bax and interleukin-1beta-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression.

@article{Rueda1997IncreasedBA,
  title={Increased bax and interleukin-1beta-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression.},
  author={Bo Ruben Rueda and Kim I. Tilly and Ihab W Botros and Prof. Dr. F. Jolly and Thomas Rask Hansen and Patricia B. Hoyer and Jonathan L. Tilly},
  journal={Biology of reproduction},
  year={1997},
  volume={56 1},
  pages={186-93}
}
Recent reports have demonstrated that prostaglandin F2alpha-induced generation of reactive oxygen species or their intermediates inhibits progesterone synthesis and may also serve as a trigger for apoptosis in the corpus luteum (CL). BCL-2, an inhibitor of apoptosis in a wide variety of cell types, has been reported to prevent oxidative stress-induced cell death. Thus, the present studies were conducted to determine whether levels of mRNA encoding BCL-2 and related members of this gene family… CONTINUE READING

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