Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low‐intensity exercise with negative energy balance

@inproceedings{Moberg2017IncreasedAS,
  title={Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low‐intensity exercise with negative energy balance},
  author={Marcus Moberg and Gina Hendo and Madelene Jakobsson and C Mikael Mattsson and Elin Ekblom-Bak and Mikael Salomonsson Flockhart and Marjan Pont{\'e}n and Karin S{\"o}derlund and Bj{\"o}rn Ekblom},
  booktitle={Physiological reports},
  year={2017}
}
Little is known about the molecular regulation of skeletal muscle protein turnover during exercise in field conditions where energy is intake inadequate. Here, 17 male and 7 female soldiers performed an 8 days long field-based military operation. Vastus lateralis muscle biopsies, in which autophagy, the ubiquitin-proteasome system, and the mTORC1 signaling pathway were studied, were collected before and after the operation. The 187 h long operation resulted in a 15% and 29% negative energy… CONTINUE READING
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