Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment.

@article{An2016IncreasedAI,
  title={Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment.},
  author={Ying Hui An and Wenjia Liu and Peng Xue and Yongjie Zhang and Qin-tao Wang and Yan Jin},
  journal={Journal of clinical periodontology},
  year={2016},
  volume={43 7},
  pages={
          618-25
        }
}
OBJECTIVE Autophagy, which provides a mechanism for turnover cellular organelles and proteins through a lysosome-dependent degradation pathway, has been related to the pathogenesis of inflammatory disorders and other diseases. Therefore, the aim of this research was to study the role of autophagy in periodontal ligament stem cells (PDLSCs) and provide a new strategy for treatment or prevention of periodontitis. METHODS We used immunohistochemistry to detect the LC3 expression in periodontal… CONTINUE READING
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