Increased asymmetric dimethylarginine level after antiepileptic drug treatment may be independent of the changes in plasma homocysteine level

@article{z2012IncreasedAD,
  title={Increased asymmetric dimethylarginine level after antiepileptic drug treatment may be independent of the changes in plasma homocysteine level},
  author={Oğuzhan {\"O}z and Mehmet Y{\"u}cel and Hakan Akg{\"u}n and Zeki G{\"o}kçil and Zeki Odabaşı},
  journal={Seizure},
  year={2012},
  volume={21}
}
2 Citations

Asymmetric Dimethylarginine as a Vascular Risk Factor in Antiepileptic Drug Treated Individuals

Elevated asymmetric Dimethylarginine levels may be responsible for the increased cardiovascular risk in patients with epilepsy who are receiving antiepileptic drug therapy, and the role of asymmetric dimethylarg inine should be considered in children treated with antiePileptic drugs.

References

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Asymmetric dimethylarginine and total homocysteine in plasma after oral methionine loading

No clear evidence was found to support the supposition that methionine‐induced hyperhomocysteinaemia may be accompanied by elevated levels of ADMA, an endogenous competitive NO‐synthase inhibitor that may represent an alternative pathogenic mechanism for homocysteine‐associated impairment of endothelial NO‐dependent functions.

Hyperhomocysteinaemia is not associated with increased levels of asymmetric dimethylarginine in patients with ischaemic heart disease

This work aimed to investigate whether elevated levels of plasma total homocysteine are associated with high plasma levels of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, and whether reduction of plasmatotal homocystine levels by folate and vitamin B supplementation lowers plasma concentration of asymmetrical dimethyl arginine.

E-mail address: oz_oguzhan@yahoo.com (O

  • E-mail address: oz_oguzhan@yahoo.com (O

Turkey Mehmet Yü cel Turkish Air Force Academy, I ˙ stanbul, Turkey Hakan Akgü n Etimesgut Military Hospital

  • Neurology Service