Increased aspartic acid release from the iron-induced epileptogenic focus.

@article{Janjua1990IncreasedAA,
  title={Increased aspartic acid release from the iron-induced epileptogenic focus.},
  author={Najma Aslam Janjua and Akihisa Mori and Midori Hiramatsu},
  journal={Epilepsy research},
  year={1990},
  volume={6 3},
  pages={215-20}
}
Evidence has been growing in recent years for the involvement of excitatory neurotransmitter amino acids in the etiology of epilepsy. The precise mechanism of this involvement, however, remains unknown. In the present study, in vitro release and uptake of [3H]aspartic acid and [3H]glutamic acid were investigated in focal cerebral cortex in the iron-induced model of post-traumatic epilepsy in the rat. The animals were injected with FeCl3 or saline into the cerebral cortex and release and uptake… CONTINUE READING