Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk

  title={Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk},
  author={Nicholas L. Mills and J J Miller and Atul Anand and Simon D. Robinson and G A Frazer and D. Anderson and L Breen and Ian B. Wilkinson and Carmel M. McEniery and Ken Donaldson and David E. Newby and W. MacNee},
  pages={306 - 311}
Rationale: Chronic obstructive pulmonary disease (COPD) is associated with a 2–3-fold increase in the risk of ischaemic heart disease, stroke and sudden death. The mechanisms responsible for this association are not clear and appear to be independent of smoking history. Objective: We test the hypothesis that patients with COPD have increased arterial stiffness and blood pressure in comparison with age and smoking matched controls. Methods: In a prospective case control study, we recruited 102… 

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