Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study

@article{Sheline2001IncreasedAR,
  title={Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study},
  author={Y. Sheline and D. Barch and J. Donnelly and J. Ollinger and M. Mintun},
  journal={Biological Psychiatry},
  year={2001},
  volume={50},
  pages={651-658}
}
  • Y. Sheline, D. Barch, +2 authors M. Mintun
  • Published 2001
  • Medicine, Psychology
  • Biological Psychiatry
  • BACKGROUND The amygdala has a central role in processing emotions, particularly fear. During functional magnetic resonance imaging (fMRI) amygdala activation has been demonstrated outside of conscious awareness using masked emotional faces. METHODS We applied the masked faces paradigm to patients with major depression (n = 11) and matched control subjects (n = 11) during fMRI to compare amygdala activation in response to masked emotional faces before and after antidepressant treatment. Data… CONTINUE READING

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