Increased alpha1-adrenergic activity in the rat bladder by depletion of ovarian hormones.


PURPOSE It is possible that postmenopausal loss of ovarian hormones leads to sensitization and/or over expression of alpha1-adrenergic receptors. The objective of this study was to determine whether ovariectomy enhances efferent transmission and, hence, increases contractility in the rat bladder by increasing alpha1-adrenergic receptors. MATERIALS AND… (More)