Increased adenylyl cyclase type 1 mRNA, but not adenylyl cyclase type 2 in the rat hippocampus following antidepressant treatment

@article{Jensen2000IncreasedAC,
  title={Increased adenylyl cyclase type 1 mRNA, but not adenylyl cyclase type 2 in the rat hippocampus following antidepressant treatment},
  author={J. Bitsch Jensen and Jens Damsgaard Mikkelsen and Arne M\ork.},
  journal={European Neuropsychopharmacology},
  year={2000},
  volume={10},
  pages={105-111}
}
The adenylyl cyclase (AC) system is affected by several types of antidepressant treatments, and increased activity in this system is linked to the therapeutic action of antidepressants. The present study was undertaken to compare the effects of single-dose and long-term treatment with the selective serotonin reuptake inhibitor, citalopram (10 mg/kg, i.p.), on the AC system in the male rat brain of Wistar rats. Furthermore, we compared the effects of long-term citalopram and lithium treatments… CONTINUE READING

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