Increased activation of stromal interaction molecule-1/Orai-1 in aorta from hypertensive rats: a novel insight into vascular dysfunction.

Abstract

Disturbances in the regulation of cytosolic calcium (Ca(2+)) concentration play a key role in the vascular dysfunction associated with arterial hypertension. Stromal interaction molecules (STIMs) and Orai proteins represent a novel mechanism to control store-operated Ca(2+) entry. Although STIMs act as Ca(2+) sensors for the intracellular Ca(2+) stores… (More)
DOI: 10.1161/HYPERTENSIONAHA.108.124404

Topics

6 Figures and Tables

Cite this paper

@article{Giachini2009IncreasedAO, title={Increased activation of stromal interaction molecule-1/Orai-1 in aorta from hypertensive rats: a novel insight into vascular dysfunction.}, author={Fernanda R.C. Giachini and Chin-Wei Chiao and Fernando Silva Carneiro and Victor Vitorino Lima and Zidonia N. Carneiro and Anne McLaren Dorrance and Rita de C{\'a}ssia Aleixo Tostes and Robert Clinton Webb}, journal={Hypertension}, year={2009}, volume={53 2}, pages={409-16} }