Increased acellular and cellular surface mineralization induced by nanogrooves in combination with a calcium-phosphate coating.

@article{Klymov2016IncreasedAA,
  title={Increased acellular and cellular surface mineralization induced by nanogrooves in combination with a calcium-phosphate coating.},
  author={Alexey Klymov and Jiankang Song and Xinjie Cai and Joost te Riet and Sander C G Leeuwenburgh and John A. Jansen and X Frank Walboomers},
  journal={Acta biomaterialia},
  year={2016},
  volume={31},
  pages={
          368-377
        }
}
UNLABELLED The current work evaluated the influence of nanoscale surface-topographies in combination with a calcium phosphate (CaP) coating on acellular and cellular surface mineralization. Four groups of substrates were produced, including smooth, grooved (940nm pitch, 430nm groove width, 185nm depth), smooth coated, and grooved coated. The substrates were characterized by scanning/transmission electron microscopy and atomic force microscopy. Osteoblast-like MC3T3 cells were cultured on the… CONTINUE READING