Increased WNT6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patients.

@article{Zhang2015IncreasedWE,
  title={Increased WNT6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patients.},
  author={Lin Zhang and G. X.-Z. Yuan and Yujing Fang and Miaozhen Qiu and Jian-hua Lin and Jian Sun and Dajun Yang},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 9},
  pages={11421-7}
}
WNT proteins are a family of secreted, cysteine-rich proteins containing 19 members. Signaling through WNT proteins is reported to be involved in carcinogenesis and cancer progression of gastrointestinal tumors, such as gastric cancer and colon cancer. The expression status of WNT6 in ESCCs and their clinico-prognostic significances remain to be elucidated. In this study, One-hundred and thirty-six patients with ESCC were explored. Paraffin-embedded tumor sections were stained with WNT6… CONTINUE READING