Increased Toll-like receptor-2 expression on nonclassic CD16+ monocytes from patients with inflammatory stage of Eales' disease.

  title={Increased Toll-like receptor-2 expression on nonclassic CD16+ monocytes from patients with inflammatory stage of Eales' disease.},
  author={Aditi Sen and Imran Hussain Chowdhury and Debanjan Mukhopadhyay and Suman Kalyan Paine and Amrita Mukherjee and Lakshmi Kanta Mondal and Mitali Chatterjee and Basudev Bhattacharya},
  journal={Investigative ophthalmology \& visual science},
  volume={52 9},
PURPOSE To identify the distribution, differential Toll-like receptor (TLR) expression, and functional contribution of monocyte subpopulations in the inflammatory stage of Eales' disease (ED). METHODS Peripheral blood mononuclear cells were isolated from nine patients during the inflammatory stage of ED and nine age- and sex-matched healthy controls. The expression of CD14, CD16, TLR-2, and TLR-4 on monocytes was measured by flow cytometry. The CD14⁺, CD16⁻, and CD16⁺ monocyte populations… 
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