Increased Serum and Musculotendinous Fibrogenic Proteins following Persistent Low-Grade Inflammation in a Rat Model of Long-Term Upper Extremity Overuse

@inproceedings{Gao2013IncreasedSA,
  title={Increased Serum and Musculotendinous Fibrogenic Proteins following Persistent Low-Grade Inflammation in a Rat Model of Long-Term Upper Extremity Overuse},
  author={Helen G. L. Gao and Paul W. Fisher and Alex G. Lambi and Christine K. Wade and Ann E. Barr-Gillespie and Steven N. Popoff and Mary F. Barbe},
  booktitle={PloS one},
  year={2013}
}
We examined the relationship between grip strength declines and muscle-tendon responses induced by long-term performance of a high-repetition, low-force (HRLF) reaching task in rats. We hypothesized that grip strength declines would correlate with inflammation, fibrosis and degradation in flexor digitorum muscles and tendons. Grip strength declined after training, and further in weeks 18 and 24, in reach limbs of HRLF rats. Flexor digitorum tissues of reach limbs showed low-grade increases in… CONTINUE READING
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