Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder

@article{Tyrer2016IncreasedSV,
  title={Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder},
  author={A E Tyrer and Robert D. Levitan and Sylvain Houle and Alan A. Wilson and Jos{\'e} N. Nobrega and Jeffrey H. Meyer},
  journal={Neuropsychopharmacology},
  year={2016},
  volume={41},
  pages={2447-2454}
}
Seasonal affective disorder (SAD) is highly prevalent with rates of 1–6% and greater prevalence at more extreme latitudes; however, there are almost no direct brain investigations of this disorder. In health, serotonin transporter binding potential (5-HTT BPND), an index of 5-HTT levels, is greater throughout the brain in fall-winter compared with spring-summer. We hypothesized that in SAD, this seasonal variation would be greater in brain regions containing structures that regulate affect such… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Seasonal affective disorder, winter type: current insights and treatment options

  • Psychology research and behavior management
  • 2016
VIEW 13 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Perspectives in affective disorders: Clocks and sleep.

  • The European journal of neuroscience
  • 2019
VIEW 3 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

An overview of epidemiological studies on seasonal affective disorder

A Magnusson
  • Acta Psychiatr Scand
  • 2000
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Elevated monoamine

G Rajkowska, RD Levitan
  • 2014