Increased Regulatory T Cells in Spleen during Experimental Autoimmune Uveoretinitis.

Abstract

PURPOSE To investigate the role of Foxp3-positive regulatory T cells in the development of experimental autoimmune uveoretinitis (EAU). METHODS B10RIII mice were immunized with 50 microg IRBP(161-180) in complete Freund's adjuvant (CFA) to induce EAU. EAU was evaluated clinically and pathologically on days 0, 7, 14, 21, and 28. Foxp3 mRNA levels were… (More)
DOI: 10.3109/09273940903414525

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