Increased MUC6 apomucin expression is a characteristic of reactive biliary epithelium in chronic viral hepatitis.

@article{Sasaki1998IncreasedMA,
  title={Increased MUC6 apomucin expression is a characteristic of reactive biliary epithelium in chronic viral hepatitis.},
  author={Motoko Sasaki and Yasuni Nakanuma and Samuel B. Ho and Young Ju Kim},
  journal={The Journal of pathology},
  year={1998},
  volume={185 2},
  pages={191-8}
}
The significance of bile ductular proliferation in the progression of various hepatobiliary diseases remains unclear. Increased expression of MUC6 apomucin, a major gastric mucin, has previously been noticed in proliferating bile ductules in chronic viral hepatitis. The purpose of the present study was to characterize MUC6 apomucin and mRNA expression in 35 histologically 'normal livers', 47 livers with chronic viral hepatitis, 28 with primary biliary cirrhosis, and seven with extrahepatic… CONTINUE READING