Increased MICs of gamithromycin and tildipirosin in the presence of the genes erm(42) and msr(E)-mph(E) for bovine Pasteurella multocida and Mannheimia haemolytica.

@article{Michael2012IncreasedMO,
  title={Increased MICs of gamithromycin and tildipirosin in the presence of the genes erm(42) and msr(E)-mph(E) for bovine Pasteurella multocida and Mannheimia haemolytica.},
  author={Geovana Brenner Michael and Christopher Eidam and Kristina Kadlec and Kerstin Meyer and Michael T. Sweeney and Robert W. Murray and Jeffrey L. Watts and Stefan Schwarz},
  journal={The Journal of antimicrobial chemotherapy},
  year={2012},
  volume={67 6},
  pages={1555-7}
}
Sir, Bovine respiratory disease (BRD) is one of the economically most important diseases in animal production, with global losses of the feedlot industry due to BRD being estimated to be over US$ 3 billion per year. Antimicrobial agents, particularly macrolides, are commonly used to combat bacteria involved in BRD, such as Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. After the approval of the 16-membered macrolide tilmicosin (Micotil) in 1992 and the 15-membered… CONTINUE READING