Increased LFA-1 Expression in Intestines of Rats with GVHD After Small Bowel Transplantation

Abstract

Experimental graft-versus-host disease (GVHD)causes immune-mediated intestinal injury. The adhesionmolecule lymphocyte function associated antigen-1(LFA-1) is involved in leukocyte homing to areas of inflammatory injury. Our hypothesis was thatLFA-1 is increased in the GVHD injured small bowel andcolon. We found that animals with GVHD caused byauxiliary… (More)
DOI: 10.1023/A:1018821431151

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