Increased Iron Deposition on Brain Quantitative Susceptibility Mapping Correlates with Decreased Cognitive Function in Alzheimer's Disease.

@article{Du2018IncreasedID,
  title={Increased Iron Deposition on Brain Quantitative Susceptibility Mapping Correlates with Decreased Cognitive Function in Alzheimer's Disease.},
  author={Lei Du and Zifang Zhao and Ailing Cui and Yijiang Zhu and Lu Zhang and Jing Liu and Sumin Shi and Chao Fu and Xiaowei Han and Wenwen Gao and TianBin Song and Lizhi Xie and Lei Wang and Shilong Sun and Runcai Guo and Guolin Ma},
  journal={ACS chemical neuroscience},
  year={2018},
  volume={9 7},
  pages={
          1849-1857
        }
}
The excessive accumulation of iron in deep gray structures is an important pathological characteristic in patients with Alzheimer's disease (AD). Quantitative susceptibility mapping (QSM) is more specific than other imaging-based iron measurement modalities and allows noninvasive assessment of tissue magnetic susceptibility, which has been shown to correlate well with brain iron levels. This study aimed to investigate the correlations between the magnetic susceptibility values of deep gray… CONTINUE READING