Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes

Abstract

Type 1 diabetes (T1D) results from a complex interplay between genetic susceptibility and environmental factors that have been implicated in the pathogenesis of disease both as triggers and potentiators of β-cell destruction. CD8 T cells are the main cell type found in human islets, and they have been shown in vitro to be capable of killing β-cells… (More)
DOI: 10.2337/db14-0549

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Cite this paper

@inproceedings{RodrguezCalvo2014IncreasedIC, title={Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes}, author={Teresa Rodr{\'i}guez-Calvo and Olov Ekwall and Natalie Amirian and Jose Zapardiel-Gonzalo and Matthias G von Herrath}, booktitle={Diabetes}, year={2014} }