Increased IL-6 and IL-8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters.

@article{Takizawa1997IncreasedIA,
  title={Increased IL-6 and IL-8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters.},
  author={Hajime Takizawa and Masaaki Satoh and Hiroko Okazaki and Goro Matsuzaki and Noboru Suzuki and Akira Ishii and Matsunobu Suko and Hirokazu Okudaira and Yuriko Morita and Kazuhiko Ito},
  journal={Clinical and experimental immunology},
  year={1997},
  volume={107 1},
  pages={175-81}
}
A variety of cytokines have been implicated in the pathogenesis of pulmonary sarcoidosis, but the exact roles of IL-6 and IL-8 are not yet clear. We studied these cytokine levels in BALF from patients with pulmonary sarcoidosis, idiopathic pulmonary fibrosis (IPF), systemic screlosis (SSc) with interstitial lung disease and control subjects. IL-6 and IL-8 levels were significantly elevated in sarcoidosis, IPF and SSc with interstitial lung disease compared with control subjects. Subjects with… CONTINUE READING

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