Increased Glyoxalase-1 Levels in Fkbp5 Knockout Mice Caused by Glyoxalase-1 Gene Duplication

@inproceedings{Kollmannsberger2013IncreasedGL,
  title={Increased Glyoxalase-1 Levels in Fkbp5 Knockout Mice Caused by Glyoxalase-1 Gene Duplication},
  author={Lorenz K. Kollmannsberger and Nils Christian Gassen and Andrea Bultmann and Jakob Hartmann and Peter Weber and Mathias V Schmidt and Theo Rein},
  booktitle={G3},
  year={2013}
}
Fkbp5 is genetically linked to stress-related diseases. Fkbp5 knockout mice are available and widely used to explore the role of Fkbp5 in health and disease. We found that these mice carry a gene duplication of glyoxylase-1, which explains why glyoxylase-1 levels are increased in the Fkbp5 knockout mice.