Increased Frataxin Levels Protect Retinal Ganglion Cells After Acute Ischemia/Reperfusion in the Mouse Retina In Vivo.

Abstract

PURPOSE The mitochondrial protein frataxin (FXN) is highly expressed in metabolically active tissues and has been shown to improve cell survival in response to oxidative stress after ischemia. Retinal ischemia/hypoxia is a complication of ocular diseases such as diabetic retinopathy and glaucoma. There are no effective therapeutic approaches currently… (More)
DOI: 10.1167/iovs.16-19260

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Cite this paper

@article{Schultz2016IncreasedFL, title={Increased Frataxin Levels Protect Retinal Ganglion Cells After Acute Ischemia/Reperfusion in the Mouse Retina In Vivo.}, author={Rowena A Schultz and Otto W. Witte and Christian W. Schmeer}, journal={Investigative ophthalmology & visual science}, year={2016}, volume={57 10}, pages={4115-24} }