Increased Expression of the Large GTPase Dynamin 2 Potentiates Metastatic Migration and Invasion of Pancreatic Ductal Carcinoma

Abstract

Pancreatic ductal tumors invade local parenchyma and metastasize to distant organs. Src-mediated tyrosine kinase signaling pathways promote pancreatic ductal adenocarcinoma (PDAC) metastasis, though the molecular mechanisms supporting this invasive process are poorly understood and represent important and novel therapeutic targets. The large GTPase Dynamin… (More)
DOI: 10.1038/onc.2011.329

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@inproceedings{Eppinga2012IncreasedEO, title={Increased Expression of the Large GTPase Dynamin 2 Potentiates Metastatic Migration and Invasion of Pancreatic Ductal Carcinoma}, author={Robbin D. Eppinga and Eugene W Krueger and Shaun G. Weller and Lizhi Zhang and Hong Cao and Mark A. McNiven}, booktitle={Oncogene}, year={2012} }