Increased Expression of EMMPRIN and VEGF in the Rat Brain after Gamma Irradiation

Abstract

The extracellular matrix metalloproteinase inducer (EMMPRIN) has been known to play a key regulatory role in pathological angiogenesis. A elevated activation of vascular endothelial growth factor (VEGF) following radiation injury has been shown to mediate blood-brain barrier (BBB) breakdown. However, the roles of EMMPRIN and VEGF in radiation-induced brain… (More)
DOI: 10.3346/jkms.2012.27.3.291

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