Increased Expression of Cathepsin L: A Novel Independent Prognostic Marker of Worse Outcome in Hepatocellular Carcinoma Patients


OBJECTIVES To investigate the expression and role of Cathepsin L (CTSL) in Hepatocellular carcinoma (HCC) tissue and cell line (MHCC-97H), and to evaluate the clinical and prognostic significance of CTSL protein in patients with HCC. METHODS The expression of CTSL was examined in HCC tissue and MHCC-97H cells by Western-blotting, Real-time PCR and… (More)
DOI: 10.1371/journal.pone.0112136


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