Increased DNA damage and oxidative stress in patients with cutaneous leishmaniasis.

@article{Kocyigit2005IncreasedDD,
  title={Increased DNA damage and oxidative stress in patients with cutaneous leishmaniasis.},
  author={Abdurrahim Kocyigit and Huseyin Keles and Şahbettin Selek and Salih Guzel and Hakim Çelik and Ozcan Erel},
  journal={Mutation research},
  year={2005},
  volume={585 1-2},
  pages={
          71-8
        }
}
Cutaneous leishmaniasis (CL) is a chronic infectious and granulomatous disease caused by the Leishmania parasite that invades the skin. Reactive oxygen and nitrogen species (ROS and RNS) produced during an inflammatory response are an important part of host-defense strategies of organisms to kill the parasite. However, it is not well known whether these intermediates cause DNA damage in CL patients. We investigated the effect of Leishmania infection on basal levels of DNA strand breaks and on… CONTINUE READING

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