Increased Cycling Cell Numbers and Stem Cell Associated Proteins as Potential Biomarkers for High Grade Human Papillomavirus+ve Pre-Neoplastic Cervical Disease

@inproceedings{Canham2014IncreasedCC,
  title={Increased Cycling Cell Numbers and Stem Cell Associated Proteins as Potential Biomarkers for High Grade Human Papillomavirus+ve Pre-Neoplastic Cervical Disease},
  author={Maurice Canham and Chara Charsou and June Stewart and Sharon Moncur and Laura J. Hoodless and Ramya Bhatia and Duanduan Cong and Heather Ann Cubie and Camille Busby-Earle and Alistair Williams and Victoria McLoughlin and John D M Campbell and Kate Cuschieri and Sarah E. M. Howie},
  booktitle={PloS one},
  year={2014}
}
High risk (oncogenic) human papillomavirus (HPV) infection causes cervical cancer. Infections are common but most clear naturally. Persistent infection can progress to cancer. Pre-neoplastic disease (cervical intraepithelial neoplasia/CIN) is classified by histology (CIN1-3) according to severity. Cervical abnormalities are screened for by cytology and/or detection of high risk HPV but both methods are imperfect for prediction of which women need treatment. There is a need to understand the… CONTINUE READING
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