Increased CCR4 expression on circulating CD4(+) T cells in ankylosing spondylitis, rheumatoid arthritis and systemic lupus erythematosus.

@article{Yang2004IncreasedCE,
  title={Increased CCR4 expression on circulating CD4(+) T cells in ankylosing spondylitis, rheumatoid arthritis and systemic lupus erythematosus.},
  author={Pingting Yang and Hiroshi Kasai and Li Juan Zhao and Wei Ge Xiao and Fuminori Tanabe and M Ito},
  journal={Clinical and experimental immunology},
  year={2004},
  volume={138 2},
  pages={
          342-7
        }
}
Previous studies have suggested that CCR4 is particularly important in the selective recruitment of various subsets of leucocytes in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). In this study, we examined the percentage of CD4(+)/CCR4(+) T cells within circulating lymphocytes in active ankylosing spondylitis (AS), RA and SLE patients. The clinical significance of CCR4 expression as well as possible associations between the expression and serum levels of tumour necrosis… CONTINUE READING

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