Increased Arterial Distensibility in Postmenopausal Hypertensive Women with and Without Hormone Replacement Therapy after Acute Administration of the Ace Inhibitor Moexipril

@article{Blacher1998IncreasedAD,
  title={Increased Arterial Distensibility in Postmenopausal Hypertensive Women with and Without Hormone Replacement Therapy after Acute Administration of the Ace Inhibitor Moexipril},
  author={Jacques Blacher and Jocelyne Raison and Guy Amah and A L Schiemann and Michael Stimpel and Michel E. Safar},
  journal={Cardiovascular Drugs and Therapy},
  year={1998},
  volume={12},
  pages={409-414}
}
Menopause and essential hypertension are associated with a decreased compliance and distensibility of the arteries. ACE inhibitors have been shown to improve arterial distensibility. Hormone replacement therapy (HRT), especially estrogens, could have a positive influence through their atheroprotective, vasodilative, and blood pressure–lowering effect. The vascular interactions of HRT and ACE inhibitors, like moexipril hydrochloride, have not been investigated so far. This trial was intended to… CONTINUE READING

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