Increased ATP production during long-term brain ischemia in rats in the presence of propentofylline.

@article{Plaschke1998IncreasedAP,
  title={Increased ATP production during long-term brain ischemia in rats in the presence of propentofylline.},
  author={Konstanze Plaschke and Hubert J. Bardenheuer and Markus Alexander Weigand and Eike Martin and Siegfried Hoyer},
  journal={European journal of pharmacology},
  year={1998},
  volume={349 1},
  pages={33-40}
}
Forty adult rats were subjected to stepwise two- and four-brain vessel occlusion and propentofylline 25 mg/day per kilogram body weight was intraperitoneally administered for 1 week or 3 weeks. Adenosine 5'-triphosphate, creatine phosphate, adenosine 5'-diphosphate and adenosine were determined in rat parietotemporal cortex by high-pressure liquid chromatography; lactate and pyruvate were measured spectrophotometrically. Stepwise and permanent long-term brain vessel occlusion gradually reduced… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-2 of 2 extracted citations

Similar Papers

Loading similar papers…