Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone.

@article{Ardanuy2006IncreaseOT,
  title={Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone.},
  author={Carmen Ardanuy and Asunci{\'o}n Fenoll and Sonsoles Berr{\'o}n and Laura Calatayud and Josefina Li{\~n}ares},
  journal={Antimicrobial agents and chemotherapy},
  year={2006},
  volume={50 9},
  pages={3162-5}
}
Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS(B) phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% (P < 0.01). Clonal dissemination of mef(E)-carrying strains of serotype 14 variant of the Spain(9V)-3 clone was the major contributor to this increase. 

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