Increase of preprotachykinin mRNA in the uninjured mandibular neurons after rat infraorbital nerve transection.

@article{Tsuzuki2003IncreaseOP,
  title={Increase of preprotachykinin mRNA in the uninjured mandibular neurons after rat infraorbital nerve transection.},
  author={Kenzo Tsuzuki and T OSHIHIRO O DA Fukuoka and Masafumi Sakagami and Koichi Noguchi},
  journal={Neuroscience letters},
  year={2003},
  volume={345 1},
  pages={57-60}
}
An increasing number of studies are suggesting that the adjacent uninjured primary afferents contribute to the mechanisms of neuropathic pain following peripheral nerve injury. In this study, we report that transection of the infraorbital nerve, a major branch of the maxillary nerve, causes exaggerated face grooming to normally innocuous mechanical stimuli in the skin territory of the uninjured mandibular nerve, and increases the expression of preprotachykinin mRNA in the primary afferent… CONTINUE READING

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