Increase of oxygen consumption during a progressive decrease of ventilatory support is lower in patients failing the trial in comparison with those who succeed.

@article{Bellani2010IncreaseOO,
  title={Increase of oxygen consumption during a progressive decrease of ventilatory support is lower in patients failing the trial in comparison with those who succeed.},
  author={Giacomo Bellani and Giuseppe Foti and Ester Spagnolli and Manuela Milan and Alberto Zanella and Massimilano Greco and Nicol{\'o} Patroniti and Antonio Pesenti},
  journal={Anesthesiology},
  year={2010},
  volume={113 2},
  pages={378-85}
}
BACKGROUND The aim of this study was to test the hypothesis that, during weaning from mechanical ventilation, when the pressure support level is reduced, oxygen consumption increases more in patients unable to sustain the decrease in ventilatory assistance (weaning failure). METHODS Patients judged eligible for weaning were enrolled. Starting from 20 cm H2O, pressure support was decreased in 4-cm H2O steps, lasting 10 min each, until 0 cm H2O; this level was kept for 1 h. The average oxygen… CONTINUE READING

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Weaning from mechanical ventilation.

The European respiratory journal • 2007
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