Increase of myometrial activity correlated with variations in 17 beta-estradiol and progesterone uterine concentrations in mid-term pregnant rat: estrogen agonist effect of 4-hydroxytamoxifen.


The objective of this investigation was to examine the effects of 4-hydroxytamoxifen on the uterine activity. For this, we evaluated the electrical activity of the myometrium, chronically, in conscious unrestrained rats at mid-pregnancy. We also examined the tissular progesterone and 17 beta-estradiol concentrations in the myometrium and uterus 6 hours… (More)


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