Increase of fidelity of polypeptide synthesis by spermidine in eukaryotic cell-free systems.

Abstract

The mechanism of spermidine-induced increase of fidelity of polypeptide synthesis in a wheat germ cell-free system has been studied. It was found that the increase of fidelity in the presence of spermidine occurred mainly at the level of binding of aminoacyl-tRNA to ribosomes, that reduction of misreading was more marked at the 5'-base than at the 3'-base… (More)

Topics

Cite this paper

@article{Igarashi1982IncreaseOF, title={Increase of fidelity of polypeptide synthesis by spermidine in eukaryotic cell-free systems.}, author={Kazuei Igarashi and Shin Hashimoto and Ai Miyake and Kenji Kashiwagi and Shigehisa Hirose}, journal={European journal of biochemistry}, year={1982}, volume={128 2-3}, pages={597-604} }