Increase of eicosapentaenoic acid in thraustochytrids through thraustochytrid ubiquitin promoter-driven expression of a fatty acid {delta}5 desaturase gene.

@article{Kobayashi2011IncreaseOE,
  title={Increase of eicosapentaenoic acid in thraustochytrids through thraustochytrid ubiquitin promoter-driven expression of a fatty acid \{delta\}5 desaturase gene.},
  author={Takumi Kobayashi and Keishi Sakaguchi and Takanori Matsuda and Eriko Abe and Yoichiro Hama and Masahiro Hayashi and Daiske Honda and Yuji Okita and Shinichi Sugimoto and Nozomu Okino and Makoto Ito},
  journal={Applied and environmental microbiology},
  year={2011},
  volume={77 11},
  pages={3870-6}
}
Thraustochytrids, marine protists known to accumulate polyunsaturated fatty acids (PUFAs) in lipid droplets, are considered an alternative to fish oils as a source of PUFAs. The major fatty acids produced in thraustochytrids are palmitic acid (C(16:0)), n - 6 docosapentaenoic acid (DPA) (C(22:5)(n) (- 6)), and docosahexaenoic acid (DHA) (C(22:6)(n) (- 3)), with eicosapentaenoic acid (EPA) (C(20:5)(n) (- 3)) and arachidonic acid (AA) (C(20:4)(n) (- 6)) as minor constituents. We attempted here to… CONTINUE READING

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