Increase in oxidative stress and mitochondrial impairment in hypothalamus of streptozotocin treated diabetic rat: Antioxidative effect of Withania somnifera.

@article{Parihar2016IncreaseIO,
  title={Increase in oxidative stress and mitochondrial impairment in hypothalamus of streptozotocin treated diabetic rat: Antioxidative effect of Withania somnifera.},
  author={Priyanka Parihar and Raviraja Shetty and Pedram Ghafourifar and Mordhwaj Singh Parihar},
  journal={Cellular and molecular biology},
  year={2016},
  volume={62 1},
  pages={73-83}
}
Hypothalamus, the primary brain region for glucose sensing, is severely affected by oxidative stress in diabetes mellitus. Oxidative stress in this region of brain may cause severe impairment in neuronal metabolic functions. Mitochondria are prominent targets of oxidative stress and the combination of increased oxidative stress and mitochondrial… CONTINUE READING