Increase in neuronal nitric oxide synthase content of the gastroduodenal tract of diabetic rats

@article{Adeghate2003IncreaseIN,
  title={Increase in neuronal nitric oxide synthase content of the gastroduodenal tract of diabetic rats},
  author={Ernest Adeghate and Basel K. al-Ramadi and Akhmad Muwafik Saleh and C. Vijayarasathy and Abdul Samad Ponery and Khouloud Arafat and Frank Christopher Howarth and Taher Y. El-Sharkawy},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2003},
  volume={60},
  pages={1172-1179}
}
Abstract: This study examined the changes occurring in the pattern of distribution and expression of neuronal nitric oxide synthase (nNOS)-positive nerves in the gastroduodenal tract of streptozotocin-induced diabetic rats. The ganglion cells of the myenteric plexus of the gastric antrum of normal rats contain nNOS. We also observed nNOS-positive neurons and fibres in the myenteric plexus of the duodenum of normal rats. After the onset of diabetes, the number and intensity of staining of nNOS… CONTINUE READING

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VIEW 1 EXCERPT
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VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

Interaction between pancreatic hormones with cholecystokinin - octapeptide - evoked responses in the isolated pancreas of normal and diabetic rats

J. Singh, E. Adeghate, M. SalidoG., A. ParienteJ., O. JumaL.M.
  • Exp . Physiol .
  • 1999

Nitric oxide synthase - containing neurons in the myenteric plexus of the rat gastrointestinal tract : distribution and regional density

K. JarvinenM., J. WollmanW., A. PowrozekT., A. SchultzJ., L. PowleyT.
  • Anat . Embryol .
  • 1999

Nitric oxide synthase neurons and neuromuscular behavior of the anorectum

F. StebbingJ.
  • Ann . R . Coll . Surg . Engl .
  • 1998

Nitric oxide synthase ( NOS ) expression in the myen - teric plexus of streptozotocin - diabetic rats

F. WrzosH., A. Cruz, R. Polavarapu, D. Shearer, A Ouyang
  • Dig . Dis . Sci .
  • 1997