Increase in human skeletal muscle lactate produced by fenfluramine

@article{Kirby1976IncreaseIH,
  title={Increase in human skeletal muscle lactate produced by fenfluramine},
  author={M. Kirby and P. Turner},
  journal={Nature},
  year={1976},
  volume={262},
  pages={617-617}
}
  • M. Kirby, P. Turner
  • Published 1976
  • Chemistry, Medicine
  • Nature
  • OUR recent hypothesis1 that “anorectic agents” such as fenfluramine and mazindol owe at least part of their anti-obesity properties to a peripheral action on glucose metabolism by causing an increase in glucose uptake into skeletal muscle and a subsequent “wasting of calories” has been criticised2 on the grounds that there is no information on the fate of the glucose so taken up, nor convincing evidence for an increase in metabolic rate with these drugs. We have now studied the effect of… CONTINUE READING
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