Increase in efficacy of cancer radiotherapy by combination with whole-body low dose irradiation.

@article{Wu2008IncreaseIE,
  title={Increase in efficacy of cancer radiotherapy by combination with whole-body low dose irradiation.},
  author={Ning Wu and S Jin and Xue-Na Pan and Shu-zheng Liu},
  journal={International journal of radiation biology},
  year={2008},
  volume={84 3},
  pages={201-10}
}
PURPOSE Design of cancer radiotherapy protocol to reduce radiation dose and increase treatment efficacy in Lewis lung cancer (LLC) model. METHODS C57BL/6J mice subcutaneously implanted with LLC were treated by conventional radiotherapy (2Gy x 6) combined with LDWBI (low dose whole-body irradiation; the second, third, fifth and sixth local doses of 2Gy each substituted by LDWBI with 0.075Gy) and/or gene therapy (intratumor injection of pEgr-IL-18-B7.1 plasmid 24 h before the first and fourth… CONTINUE READING

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