Increase in brain-derived neurotrophic factor in first episode psychotic patients after treatment with atypical antipsychotics.

@article{GonzlezPinto2010IncreaseIB,
  title={Increase in brain-derived neurotrophic factor in first episode psychotic patients after treatment with atypical antipsychotics.},
  author={Ana M Gonz{\'a}lez-Pinto and Fernando Mosquera and Aitor Palomino and Susana Alberich and Arantza Guti{\'e}rrez and Karim Haidar and Patricia Anal{\'i}a Vega and Sara Barbeito and Agurtzane Ortiz and Carlos Matute},
  journal={International clinical psychopharmacology},
  year={2010},
  volume={25 4},
  pages={241-5}
}
Some preclinical and postmortem studies suggest that the effects of atypical antipsychotics could be mediated by brain-derived neurotrophic factor (BDNF). Olanzapine is an atypical antipsychotic with shown efficacy in psychosis treatment. The aim of this study was to compare plasma BDNF levels at baseline and after 1 year of olanzapine treatment in 18 drug-naive patients who experienced a first psychotic episode with those of 18 healthy control participants matched by age, sex, and… CONTINUE READING

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