Increase in bone volume fraction precedes architectural adaptation in growing bone.

@article{Tanck2001IncreaseIB,
  title={Increase in bone volume fraction precedes architectural adaptation in growing bone.},
  author={Esther Tanck and Jasper J. Homminga and G Harry van Lenthe and Rik Huiskes},
  journal={Bone},
  year={2001},
  volume={28 6},
  pages={650-4}
}
In mature trabecular bone, both density and trabecular orientation are adapted to external mechanical loads. Few quantitative data are available on the development of architecture and mechanical adaptation in juvenile trabecular bone. We studied the hypothesis that a time lag occurs between the adaptation of trabecular density and the adaptation of trabecular architecture during development. To investigate this hypothesis we used ten female pigs at 6, 23, 56, 104, and 230 weeks of age. Three… CONTINUE READING
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