Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus.

Abstract

We studied the expression of bcl-2 oncoprotein in the gerbil hippocampus after transient ischemia. Immunostaining using monoclonal antibody raised against bcl-2 oncoprotein revealed intense immunoreactivity in the CA1 area following 2 min of ischemia, which induced tolerance to subsequent ischemia and prevented delayed neuronal death (DND). Following… (More)

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@article{Shimazaki1994IncreaseIB, title={Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus.}, author={Kazuo Shimazaki and Akizumi Ishida and Norikazu Kawai}, journal={Neuroscience research}, year={1994}, volume={20 1}, pages={95-9} }