Increase in activin beta A mRNA in rat hippocampus during long-term potentiation.

@article{Inokuchi1996IncreaseIA,
  title={Increase in activin beta A mRNA in rat hippocampus during long-term potentiation.},
  author={Kaoru Inokuchi and Akari Kato and Keiko Hiraia and Fumio Hishinuma and Manami Inoue and Fumiko Ozawa},
  journal={FEBS letters},
  year={1996},
  volume={382 1-2},
  pages={
          48-52
        }
}
We have used mRNA differential display to isolate genes that are induced by neural activity in rat hippocampus. One of these encodes activin beta A subunit. Convulsive seizure caused by kainate significantly induced the expression of activin beta A mRNA. Furthermore high frequency stimulation (HFS) of perforant pathway, which produced a persistent long-term potentiation (LTP) (>10 h), caused a marked increase at 3 h in the level of activin beta A mRNA at the dentate gyrus of urethane… CONTINUE READING

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